Good morning, My hope....
about me: after the 3rd donation of a blastocyst (PGTa) 5BA I had a child in 2024. At that time TH1 balance was shifted and through Prograf 3mg, Granocyte, Intralipid I got pregnant. Ermap was 5.5 days. Previously in 2021 1 miscarriage in the 9th week EZS untested 5AA Blasto and otherwise 1 x no implantation. C-section with 1st child without complications, everything went well.
Current situation:
Ermap 6.5 days (test repeated 3 times)
Imap unremarkable
Coagulation test unremarkable from 2023
Blood values OK so far, except for
......Ferritin 20 mg and TPO-AK 9.8 (TSH 1.8, Ft3 2.5ngl, anti TG 0.99, ft 4 0.76)
Progesterone at 25 ngl on transfer day, after that the progesterone drops very quickly every 2 days despite highest doses, blood sample is always taken 2h after Prolutex administration
Medication:
3mg Prograf (from 10 days before transfer) prophylactically
20 mg prednisolone from transfer (10 mg before transfer) (previous transfer 10 to 15 mg)
Granocyte 34. Mio from transfer 0.3ml protocol
Intralipid on transfer day and after positive test
Ovitrelle this time on TR , TR+2, TR +4
Ass 100 mg
Folic acid 5mg
Clexane 40mg
Estradiol 10mg
Prolutex 2 x 25 mg syringe,
progesterone 3x 300 mg vaginally from transfer
B12, Lythroxin 88, iron 100mg, b6, k2, vitd3, etc....
Mucosa between 8.7 - 11mm during transfer. 3 layers. No polyps, fibroids....
I am already taking everything to cover everything and still no implantation. Not even biochemically. I am desperate.
I could only read from the forum that CD138 plasma cells/screening would still be an option. I would like to try to avoid surgical interventions as I am afraid that this could lead to adhesions. Is IVIG therapy perhaps another option? Pder Decapeptyl in the trial cycle?
I don't think it's due to the embryo, as a PGTa test has taken place. I have also already had an EMS and PGTa test, but there was no implantation.
This raises the question of what the next steps should be to avoid losing valuable embryos. Especially as the financial burden also has a limit...
I'm hoping for some tips/help..... I'm desperate.
Thank you!!!!
